PMBD
PMBD is a lysosome (Lyso) -targeting fluorescent probe. PMBD selectively and sensitively detects endogenous N-acylethanolamine amidase (NAAA), allowing real-time visual monitoring of endogenous NAAA in living cells. PMBD has a maximum absorption peak at 350 nm. After the metabolism of NAAA, the maximum absorption peak of the product AMBD shifts red to 450 nm, and a significant fluorescence emission signal appears at 550 nm [1].
Product Specifications
UNSPSC
12171500
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/pmbd.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C2C(C(NC(CCCCCCCCCCCCCCC)=O)=CC=C23)=CC=C1)N(CCN4CCOCC4)C3=O
Molecular Formula
C34H49N3O4
Molecular Weight
563.77
References & Citations
[1]Zhou L, et al. Lysosome targeting fluorescent probe for NAAA imaging and its applications in the drug development for anti-inflammatory. Int J Biol Macromol. 2024 Apr;263 (Pt 2) :130307.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Frequently Asked Questions
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