KRAS G12D inhibitor 23
Product Specifications
UNSPSC Description
KRAS G12D inhibitor 23 (compound 46-3) is a potent inhibitor of KRAS G12D, with the IC50 of 0.007 μM. KRAS G12D inhibitor 23 plays an important role in cancer research[1].
Target Antigen
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein;MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kras-g12d-inhibitor-23.html
Smiles
FC1=CC2=C(N3C[C@H]4N[C@H](CC4)C3)N=C(OC[C@@]5(C)[C@H](CCN(C5)C)C(F)F)N=C2C(F)=C1C6=CC(O)=CC7=C6C(C#C)=C(F)C=C7
Molecular Weight
651.67
References & Citations
[1]Tyligand Bioscience (Shanghai) Limited. Quinazoline compounds as KRAS inhibitors and their preparation, pharmaceutical compositions and use in the treatment of cancer. World Intellectual Property Organization, WO2024067714 A1 2024-04-04
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-158701/KRAS-G12D-inhibitor-23-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-158701/
Clinical Information
No Development Reported
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