Rabelomycin
Product Specifications
UNSPSC Description
Rabelomycin is antibiotic, which exhibits antimicrobial activity against gram positive bacteria. Rabelomycin exhibits inhibitory activity against inducible nitric oxide synthase (iNOS) with an IC50 of 63.9 μM[1][2].
Target Antigen
Antibiotic; Bacterial; NO Synthase
Type
Natural Products
Related Pathways
Anti-infection;Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Infection; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/rabelomycin.html
Smiles
O=C1C2=C(C[C@@](O)(C1)C)C=C(O)C(C(C3=C(O)C=CC=C34)=O)=C2C4=O
Molecular Weight
338.31
References & Citations
[1]Kharel MK, et al., Enzymatic total synthesis of rabelomycin, an angucycline group antibiotic. Org Lett. 2010 Jun 18;12(12):2814-7. |[2]Alvi K A, et al., Identification of inhibitors of inducible nitric oxide synthase from microbial extracts[J]. The Journal of Antibiotics, 2000, 53(5): 496-501.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-114798/Rabelomycin-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-114798/
Clinical Information
No Development Reported
CAS Number
28399-50-0
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