Rabelomycin
Rabelomycin is antibiotic, which exhibits antimicrobial activity against gram positive bacteria. Rabelomycin exhibits inhibitory activity against inducible nitric oxide synthase (iNOS) with an IC50 of 63.9 μM[1][2].
Product Specifications
CAS Number
28399-50-0
UNSPSC
12352005
Target
Antibiotic; Bacterial; NO Synthase
Type
Natural Products
Related Pathways
Anti-infection; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Infection; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/rabelomycin.html
Smiles
O=C1C2=C(C[C@@](O)(C1)C)C=C(O)C(C(C3=C(O)C=CC=C34)=O)=C2C4=O
Molecular Formula
C19H14O6
Molecular Weight
338.31
References & Citations
[1]Kharel MK, et al., Enzymatic total synthesis of rabelomycin, an angucycline group antibiotic. Org Lett. 2010 Jun 18;12 (12) :2814-7. |[2]Alvi K A, et al., Identification of inhibitors of inducible nitric oxide synthase from microbial extracts[J]. The Journal of Antibiotics, 2000, 53 (5) : 496-501.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
INOS
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