Rabelomycin

Rabelomycin is antibiotic, which exhibits antimicrobial activity against gram positive bacteria. Rabelomycin exhibits inhibitory activity against inducible nitric oxide synthase (iNOS) with an IC50 of 63.9 μM[1][2].

Product Specifications

CAS Number

[28399-50-0]

UNSPSC

12352005

Target

Antibiotic; Bacterial; NO Synthase

Type

Natural Products

Related Pathways

Anti-infection; Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Infection; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/rabelomycin.html

Smiles

O=C1C2=C(C[C@@](O)(C1)C)C=C(O)C(C(C3=C(O)C=CC=C34)=O)=C2C4=O

Molecular Formula

C19H14O6

Molecular Weight

338.31

References & Citations

[1]Kharel MK, et al., Enzymatic total synthesis of rabelomycin, an angucycline group antibiotic. Org Lett. 2010 Jun 18;12 (12) :2814-7. |[2]Alvi K A, et al., Identification of inhibitors of inducible nitric oxide synthase from microbial extracts[J]. The Journal of Antibiotics, 2000, 53 (5) : 496-501.