(S, S) -TAPI-0
(S, S) -TAPI-0 is a matrix metalloproteinase (MMP) inhibitor that inhibits the growth of Chlamydia trachomatis by inhibiting PDF enzyme activity. (S, S) -TAPI-0 can be used to study Chlamydia infection[1].
Product Specifications
CAS Number
[143457-40-3]
UNSPSC
12352005
Target
MMP
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/s-s-tapi-0.html
Smiles
C[C@@H](C(N)=O)NC([C@H](CC1=CC=C2C=CC=CC2=C1)NC(C(CC(NO)=O)CC(C)C)=O)=O
Molecular Formula
C24H32N4O5
Molecular Weight
456.53
References & Citations
[1]Balakrishnan, et al. Metalloprotease inhibitors GM6001 and TAPI-0 inhibit the obligate intracellular human pathogen Chlamydia trachomatis by targeting peptide deformylase of the bacterium. Journal of Biological Chemistry 281.24 (2006) : 16691-16699.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-136885/S-S-TAPI-0-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-136885/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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