(S, S) -TAPI-0

(S, S) -TAPI-0 is a matrix metalloproteinase (MMP) inhibitor that inhibits the growth of Chlamydia trachomatis by inhibiting PDF enzyme activity. (S, S) -TAPI-0 can be used to study Chlamydia infection[1].

Product Specifications

CAS Number

[143457-40-3]

UNSPSC

12352005

Target

MMP

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/s-s-tapi-0.html

Smiles

C[C@@H](C(N)=O)NC([C@H](CC1=CC=C2C=CC=CC2=C1)NC(C(CC(NO)=O)CC(C)C)=O)=O

Molecular Formula

C24H32N4O5

Molecular Weight

456.53

References & Citations

[1]Balakrishnan, et al. Metalloprotease inhibitors GM6001 and TAPI-0 inhibit the obligate intracellular human pathogen Chlamydia trachomatis by targeting peptide deformylase of the bacterium. Journal of Biological Chemistry 281.24 (2006) : 16691-16699.