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L-Glyceric acid

L-Glyceric acid is a mainly urinary metabolite accumulating in rare inherited metabolic disease L-glyceric aciduria. L-Glyceric acid can be used to diagnose primary hyperoxaluria type 2 (PH2) . L-Glyceric acid excretion to distinguish PH1 from PH2[1][2].

Product Specifications

CAS Number

[28305-26-2]

UNSPSC

12352211

Hazard Statement

H302-H312-H332

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/l-glyceric-acid.html

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=C(O)[C@@H](O)CO

Molecular Formula

C3H6O4

Molecular Weight

106.08

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

References & Citations

[1]Mohamed S Rashed, et al. Chiral liquid chromatography tandem mass spectrometry in the determination of the configuration of glyceric acid in urine of patients with D-glyceric and L-glyceric acidurias. Biomed Chromatogr. 2002 May;16 (3) :191-8.|[2]Bernd Hoppe, et al. A United States survey on diagnosis, treatment, and outcome of primary hyperoxaluria. Pediatr Nephrol. 2003 Oct;18 (10) :986-91.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

Human Endogenous Metabolite

Curated Selection

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