5α-Androstan-3β-ol
5α-Androstan-3β-ol (Androstan), a saturated sterol, is a CAR (constitutive androstane receptor) inverse agonist ligand. 5α-Androstan-3β-ol (Androstan) increases the AmB-channel conductance in a concentration dependent manner[1][2].
Product Specifications
CAS Number
1224-92-6
Product Name Alternative
3β-Hydroxy-5α-androstane
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/5α-androstan-3β-ol.html
Purity
98.00
Smiles
C[C@@]12[C@]3([H])[C@](CC[C@@]1([H])C[C@H](CC2)O)([H])[C@@]4([H])[C@](CC3)(CCC4)C
Molecular Formula
C19H32O
Molecular Weight
276.46
Precautions
H302, H315, H319, H335
References & Citations
[1]I Tzameli, et al. T he xenobiotic compound 1,4-bis[2- (3,5-dichloropyridyloxy) ]benzene is an agonist ligand for the nuclear receptor CAR. Mol Cell Biol. 2000 May;20 (9) :2951-8.|[2]Olga S Ostroumova, et al. Probing amphotericin B single channel activity by membrane dipole modifiers. PLoS One. 2012;7 (1) :e30261.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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