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SGN-B6A

SGN-B6A is an ADC, which targets integrin beta-6 (ITGB6) through human IgG1 monoclonal antibody Sigvotatug , and exhibits cytotoxicity against multiple integrin beta-6-positive cancer cell through mitotic inhibitor MMAE (HY-15162).

Product Specifications

UNSPSC

12352203

Target

Antibody-Drug Conjugates (ADCs) ; Integrin

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related; Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/sgn-b6a.html

Purity

99.68

Smiles

[SGN-B6A]

Molecular Weight

150000 (average)

References & Citations

[1]Lyon RP, et al., SGN-B6A: A New Vedotin Antibody-Drug Conjugate Directed to Integrin Beta-6 for Multiple Carcinoma Indications. Mol Cancer Ther. 2023 Dec 1;22 (12) :1444-1453.

Shipping Conditions

Dry Ice

Storage Conditions

-80°C, protect from light

Scientific Category

ADC Related

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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