THR-β agonist 8
THR-β agonist 8 (Compound 1) is an orally active agonist of TRα and TRβ. THR-β agonist 8 is promising for research of thyroid hormone-related diseases[1].
Product Specifications
CAS Number
[2832859-77-3]
UNSPSC
12352005
Target
Thyroid Hormone Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/thr-β-agonist-8.html
Smiles
N#CC1=NN(C2=CC(Cl)=C(C(Cl)=C2)OC3=CC=C(C(C(C)=C)=C3)O)C(NC1=O)=O
Molecular Formula
C19H12Cl2N4O4
Molecular Weight
431.23
References & Citations
[1]Sheng XK, et al. Aromatic compound, preparation method therefor, and application thereof. WO2022184177A1. 2022 September 09.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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