Aberrant tau ligand 1
Aberrant tau ligand 1 is a ligand for tau proteins with abnormal forms. Aberrant tau ligand 1 can be used for synthesis of PROTAC aberrant Tau degrader QC-01-175.
Product Specifications
CAS Number
1892461-96-9
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
PROTAC
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/aberrant-tau-ligand-1.html
Purity
99.33
Solubility
DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(O)CCC1=CC2=C(C=C1)C(C=NC=C3)=C3N2
Molecular Formula
C14H12N2O2
Molecular Weight
240.26
Precautions
H302, H315, H319, H335
References & Citations
[1]Silva MC, et al., Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models. Elife. 2019 Mar 25;8:e45457.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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