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Human CD300c / LMIR2 Protein, His Tag

CMRF35-like molecule 6 (CLM-6) is also known as CD300 antigen-like family member C, CMRF35-A1, Immunoglobulin superfamily member 16 (IgSF16), CD antigen CD300c, which belongs to the CD300 family. CLM-6 contains one Ig-like V-type (immunoglobulin-like) domain. CD300a/c RNA and surface expression were downregulated after stimulation of plasmacytoid dendritic cells (pDCs) with TLR7 and TLR9 ligands. Exogenous interferon (IFN) -alpha down-regulated CD300a/c expression. CD300a and CD300c play an important role in the cross-regulation of TNF-alpha and IFN-alpha secretion from pDCs. CD300a and CD300c are indistinguishable on the surface of NK cells.

Product Specifications

Background

CMRF35-like molecule 6 (CLM-6) is also known as CD300 antigen-like family member C, CMRF35-A1, Immunoglobulin superfamily member 16 (IgSF16), CD antigen CD300c, which belongs to the CD300 family. CLM-6 contains one Ig-like V-type (immunoglobulin-like) domain. CD300a/c RNA and surface expression were downregulated after stimulation of plasmacytoid dendritic cells (pDCs) with TLR7 and TLR9 ligands. Exogenous interferon (IFN) -alpha down-regulated CD300a/c expression. CD300a and CD300c play an important role in the cross-regulation of TNF-alpha and IFN-alpha secretion from pDCs. CD300a and CD300c are indistinguishable on the surface of NK cells.

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 18.67 kDa. The protein migrates as 26-43 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

AAH22279

Expression Region

Gly 21 - Arg 183

Host

HEK293

Target

CD300c

Conjugation

Unconjugated

Tag

C-6xHis

Source

Human

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

90%

Format

Powder

Buffer

PBS, pH7.4

Additives

Trehalose

Molecular Weight

18.67 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

100ug*10

Host or Source

HEK293

Species

Human

Protein ID

AAH22279

Preservative

Trehalose

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