D-Dopa
Product Specifications
UNSPSC Description
D-Dopa is a non-competitive, allosteric inhibitor for glutamate carboxypeptidase II (GCPII) with an IC50 of 200 nM. D-Dopa exhibits good pharmacokinetic characteristics, and low blood-brain barrier permeability in mouse model[1].
Target Antigen
Carboxypeptidase
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/d-dopa.html
Purity
97.0
Smiles
OC([C@H](N)CC1=CC(O)=C(C=C1)O)=O
Molecular Weight
197.19
References & Citations
[1]Gori SS, et al., D-DOPA Is a Potent, Orally Bioavailable, Allosteric Inhibitor of Glutamate Carboxypeptidase II. Pharmaceutics. 2022 Sep 23;14(10):2018.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W096171/D-Dopa-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W096171/
Clinical Information
No Development Reported
CAS Number
5796-17-8
Available Sizes
Curated Selection
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