Nucleoprotein (396-404)

Nucleoprotein (396-404) is the 396 to 404 fragment of lymphocytic choriomeningitis virus (LCMV). Nucleoprotein (396-404) is the H-2D(b)-restricted immunodominant epitope and can be used as a molecular model of viral antigen[1][2] .

CC[C@H](C)[C@@H](C(O)=O)NC([C@H](CC1=CC=CC=C1)NC([C@H](CCC(N)=O)NC(CNC([C@H](CC(N)=O)NC([C@H](CCC(N)=O)NC([C@H]2N(C([C@H](CCC(N)=O)NC([C@H](CC3=CC=CC=C3)N)=O)=O)CCC2)=O)=O)=O)=O)=O)=O

[1]Gairin JE, et al. Optimal lymphocytic choriomeningitis virus sequences restricted by H-2Db major histocompatibility complex class I molecules and presented to cytotoxic T lymphocytes. J Virol. 1995 Apr;69(4):2297-305.|[2]Hudrisier D, et al. Structural and functional identification of major histocompatibility complex class I-restricted self-peptides as naturally occurring molecular mimics of viral antigens. Possible role in CD8+ T cell-mediated, virus-induced autoimmune disease. J Biol Chem. 2001 Jun 1;276(22):19396-403. Epub 2001 Mar 8.