KISS1-305

KISS1-305, the Metastin/Kisspeptin analog, is a prototype peptide and a chemical probe. KISS1-305 has suboptimal KISS1R agonistic activity, and resists plasma protease degradation[1].

Product Specifications

CAS Number

[872717-97-0]

UNSPSC

12352209

Target

Kisspeptin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/kiss1-305.html

Solubility

10 mM in DMSO

Smiles

O=C(N)[C@H](CC1=CC=CC=C1)NC([C@H](CCCNC(NC)=N)NC([C@H](CC(C)C)NC(NNC([C@H](CC2=CC=CC=C2)NC([C@H](CO)NC([C@H](CC(N)=O)NC([C@@H](CC3=CC=NC=C3)NC([C@@H](CC4=CC=C(O)C=C4)N)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C56H76N16O12

Molecular Weight

1165.30

References & Citations

[1]Matsui H, et al.Chronic administration of the metastin/kisspeptin analog KISS1-305 or the investigational agent TAK-448 suppresses hypothalamic pituitary gonadal function and depletes plasma testosterone in adult male rats.Endocrinology. 2012 Nov;153 (11) :5297-308.