Anti-FBG5 Antibody

Rabbit Polyclonal Antibody specific to FBG5 (F Box 5)

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

F-box/G-domain protein 5

Gene Name

FBXO27

NCBI Gene ID

UniProt

Q8NI29

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide corresponding to amino acids 163-175 of human FBG5.

Target Antigen

F-box only protein 27

Target

FBG5

Clonality

Polyclonal

Type

Antibody

Applications

Field of Research

Neuroscience

Purification Method

Purified by Protein G affinity chromatography

Concentration

Lot Specific

Dilution

Dilute in PBS or medium that is identical to that used in the assay system.

Format

Purified

Form

Liquid

Buffer

Phosphate Buffered Saline

Function

Substrate-rPubMed:18203720}.

Additionnal Information

Immunoblotting : use at 1-5ug/ml dilution. A band of approximately 32 kDa is detected. <br><br>These are recommended concentrations. User should determine optimal concentration for their applications.

Storage Conditions

This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles.

Specificity

This antibody recognizes human, mouse, and rat FBG5.

Formulation

PBS, pH 7.4.

Buffer pH

pH 7.4

Target Background

F-box proteins, critical components of the conserved ubiquitin-protein ligase complex SCF (Skp1/Cdc53-Cullin1/F- box), recruit substrates for ubiquitination and consequent degradation through their specific protein-protein interaction domains. Novel human F-box proteins named FBG1, FBG2, FBG3, FBG4 and FBG5 constitute a subfamily of mammalian F-box proteins. FBG genes are expressed in a limited number of human tissues including kidney, liver, brain and muscle tissues.