TN14003
TN14003 is a CXCR4 inhibitor. TN14003 has antitumor activity[1].
Product Specifications
CAS Number
[368874-31-1]
UNSPSC
12352209
Target
CXCR
Type
Peptides
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tn14003.html
Solubility
10 mM in DMSO
Smiles
O=C1[C@@]2([H])N(CCC2)C([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CSSC[C@H](NC([C@@H](NC([C@@H](NC([C@@H](N1)CC3=CC=C(C=C3)O)=O)CCCNC(N)=N)=O)CCCNC(N)=O)=O)C(N[C@H](C(N)=O)CCCNC(N)=N)=O)NC([C@@H](NC([C@H](CCCNC(N)=N)NC([C@@H](N)CCCNC(N)=N)=O)=O)CC4=CC5=C(C=CC=C5)C=C4)=O)=O)CC6=CC=C(C=C6)O)=O)CCCNC(N)=O)=O)CCCCN)=O)CCCCN)=O
Molecular Formula
C90H141N33O18S2
Molecular Weight
2037.42
References & Citations
[1]Lefort S, et al. CXCR4 inhibitors could benefit to HER2 but not to triple-negative breast cancer patients. Oncogene. 2017 Mar 2;36 (9) :1211-1222.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Curated Selection
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