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TN14003

TN14003 is a CXCR4 inhibitor. TN14003 has antitumor activity[1].

Product Specifications

CAS Number

[368874-31-1]

UNSPSC

12352209

Target

CXCR

Type

Peptides

Related Pathways

GPCR/G Protein; Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tn14003.html

Solubility

10 mM in DMSO

Smiles

O=C1[C@@]2([H])N(CCC2)C([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CSSC[C@H](NC([C@@H](NC([C@@H](NC([C@@H](N1)CC3=CC=C(C=C3)O)=O)CCCNC(N)=N)=O)CCCNC(N)=O)=O)C(N[C@H](C(N)=O)CCCNC(N)=N)=O)NC([C@@H](NC([C@H](CCCNC(N)=N)NC([C@@H](N)CCCNC(N)=N)=O)=O)CC4=CC5=C(C=CC=C5)C=C4)=O)=O)CC6=CC=C(C=C6)O)=O)CCCNC(N)=O)=O)CCCCN)=O)CCCCN)=O

Molecular Formula

C90H141N33O18S2

Molecular Weight

2037.42

References & Citations

[1]Lefort S, et al. CXCR4 inhibitors could benefit to HER2 but not to triple-negative breast cancer patients. Oncogene. 2017 Mar 2;36 (9) :1211-1222.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Curated Selection

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