Human Mnk2 Protein Active

<strong>Human Mnk2 Protein Active</strong>_x000D_ <strong>Catalog number:</strong> B2014194_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 5 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 50 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20¬∞C_x000D_ <strong>Keywords:</strong> Mnk2 Protein_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MŒ©-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Manne BK, Campbell RA, Bhatlekar S, Ajanel A, Denorme F, Portier I, Middleton EA, Tolley ND, Kosaka Y, Montenont E, Guo L, Rowley JW, Bray PF, Jacob S, Fukanaga R, Proud C, Weyrich AS, Rondina MT. MAPK-interacting kinase 1 regulates platelet production, activation, and thrombosis Blood. 2022 Dec 8;140(23):2477-2489._x000D_ 2: Karampelias C, Watt K, Mattsson CL, Ruiz F, Rezanejad H, Mi J, Liu X, Chu L, Locasale JW, Korbutt GS, Rovira M, Larsson O, Andersson O. MNK2 deficiency potentiates _-cell regeneration via translational regulation Nat Chem Biol. 2022 Sep;18(9):942-953._x000D_ 3: Liu H, Gong Z, Li K, Zhang Q, Xu Z, Xu Y. SRPK1/2 and PP1 exert opposite functions by modulating SRSF1-guided MKNK2 alternative splicing in colon adenocarcinoma J Exp Clin Cancer Res. 2021 Feb 18;40(1):75._x000D_ 4: Chen BR, Wei TW, Tang CP, Sun JT, Shan TK, Fan Y, Yang TT, Li YF, Ma Y, Wang SB, Wang ZM, Wang H, Shi JZ, Liu L, Chen JW, Zhou LH, Du C, Sun R, Wang QM, Wang LS. MNK2-eIF4E axis promotes cardiac repair in the infarcted mouse heart by activating cyclin D1 J Mol Cell Cardiol. 2022 May;166:91-106._x000D_ 5: Xie J, Shen K, Jones AT, Yang J, Tee AR, Shen MH, Yu M, Irani S, Wong D, Merrett JE, Lenchine RV, De Poi S, Jensen KB, Trim PJ, Snel MF, Kamei M, Martin SK, Fitter S, Tian S, Wang X, Butler LM, Zannettino ACW, Proud CG. Reciprocal signaling between mTORC1 and MNK2 controls cell growth and oncogenesis Cell Mol Life Sci. 2021 Jan;78(1):249-270._x000D_ 6: Hu SI, Katz M, Chin S, Qi X, Cruz J, Ibebunjo C, Zhao S, Chen A, Glass DJ. MNK2 inhibits eIF4G activation through a pathway involving serine-arginine-rich protein kinase in skeletal muscle Sci Signal. 2012 Feb 14;5(211):ra14._x000D_ 7: Slentz-Kesler K, Moore JT, Lombard M, Zhang J, Hollingsworth R, Weiner MP. Identification of the human Mnk2 gene (MKNK2) through protein interaction with estrogen receptor beta Genomics. 2000 Oct 1;69(1):63-71._x000D_ 8: Scheper GC, Morrice NA, Kleijn M, Proud CG. The mitogen-activated protein kinase signal-integrating kinase Mnk2 is a eukaryotic initiation factor 4E kinase with high levels of basal activity in mammalian cells Mol Cell Biol. 2001 Feb;21(3):743-54._x000D_ 9: Merrett JE, Xie J, Psaltis PJ, Proud CG. MAPK-interacting kinase 2 (MNK2) regulates adipocyte metabolism independently of its catalytic activity Biochem J. 2020 Jul 31;477(14):2735-2754._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/33892273">10: Jin X, Yu R, Wang X, Proud CG, Jiang T. Progress in developing MNK inhibitors Eur J Med Chem. 2021 Jul 5;219:113420. </a>_x000D_ _x000D_ <strong>Products Related to Human Mnk2 Protein Active can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>