Bupivacaine (hydrochloride monohydrate)
Bupivacaine hydrochloride monohydrate is a NMDA receptor inhibitor. Bupivacaine hydrochloride monohydrate can block sodium, L-calcium, and potassium channels. Bupivacaine hydrochloride monohydrate potently blocks SCN5A channels with the IC50 of 69.5 μM. Bupivacaine hydrochloride monohydrate can be used for the research of chronic pain[1][2][3].
Product Specifications
CAS Number
[73360-54-0]
UNSPSC
12352005
Hazard Statement
H300+H310+H330
Target
Calcium Channel; iGluR; Potassium Channel; Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bupivacaine-hydrochloride-monohydrate.html
Solubility
10 mM in DMSO
Smiles
CCCCN1CCCCC1C(=O)NC2=C(C=CC=C2C)C.O.Cl
Molecular Formula
C18H31ClN2O2
Molecular Weight
342.90
Precautions
P260-P262-P264-P270-P271-P280-P284-P302+P352-P304+P340-P330-P361+P364-P405-P501
References & Citations
+
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 4
Isoform
NMDA Receptor
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