HSD17B13-IN-96
HSD17B13-IN-96 (3) is an inhibitor of 17 β-hydroxysteroid dehydrogenase (HSD17B13), and its IC50 value for estradiol is [1].
Product Specifications
CAS Number
[2849338-43-6]
UNSPSC
12352005
Target
17β-HSD
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/hsd17b13-in-96.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(C=CC=C2NC(C3=CC=C(O)C(C(F)(F)F)=N3)=O)N=CN1CC4=C(OC(F)(F)F)C=CC=C4
Molecular Formula
C23H14F6N4O4
Molecular Weight
524.37
References & Citations
[1]Joshua Odingo, et al. Hydroxypyridine hsd17b13 inhibitors and uses thereof. 2019 Apr;15 (4) :322-330. WO2022216626A1.2022-10-13.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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