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2,3-Diphosphoglyceric acid-d3 (ammonium)

2,3-Diphosphoglyceric acid-d3 ammonium (2,3-DPG-d3 ammonium) is the deuterium labeled 2,3-Diphosphoglyceric acid. 2,3-Diphosphoglyceric acid (2,3-DPG) is an intermediate of the glycolytic pathway. 2,3-Diphosphoglyceric acid stabilizes the deoxygenated form of hemoglobin by allosteric binding and facilitates oxygen release at tissue sites. 2, 3-diphosphoglyceric acid has antiparasitic activity. 2,3-Diphosphoglyceric acid can be used in the study of Alzheimer's disease (AD)[2][3][4].

Product Specifications

CAS Number

2712139-19-8

Product Name Alternative

2,3-DPG-d3 (ammonium)

UNSPSC

12352211

Target

Isotope-Labeled Compounds; Parasite

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection; Others

Field of Research

Infection; Neurological Disease

Smiles

O=P(O)(O)OC([2H])([2H])C(C(O)=O)([2H])OP(O)(O)=O.N.N.N.N.N

Molecular Formula

C3H20D3N5O10P2

Molecular Weight

354.21

References & Citations

[1]Shakil H. Merchant MD, et al. 24 - Molecular Diagnosis in Hematopathology. Hematopathology (Second Edition) .2012, 679-726. |[2]Morais I, et al. Synthetic Red Blood Cell-Specific Glycolytic Intermediate 2,3-Diphosphoglycerate (2,3-DPG) Inhibits Plasmodium falciparum Development In Vitro. Front Cell Infect Microbiol. 2022 Mar 15;12:840968.|[3]Płoszczyca K, et al. Red Blood Cell 2,3-Diphosphoglycerate Decreases in Response to a 30 km Time Trial Under Hypoxia in Cyclists. Front Physiol. 2021 Jun 15;12:670977. |[4]Kosenko EA, et al. Relationship between chronic disturbance of 2,3-diphosphoglycerate metabolism in erythrocytes and Alzheimer disease. CNS Neurol Disord Drug Targets. 2016;15 (1) :113-23.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Frequently Asked Questions

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