Polycarpine (hydrochloride)
Polycarpine hydrochloride (1a) is a broad-spectrum Mpro inhibitor (IC50 = 30 nM) that can be isolated from the Polycarpa aurata and also serves as an anti-coronaviral agent. Polycarpine hydrochloride possesses antiviral and antifungal activities, with IC50 values of 30.0 nM and 0.12 μM against SARS-CoV-2 Mpro and PEDV Mpro, respectively[1].
Product Specifications
CAS Number
[175669-29-1]
UNSPSC
12352005
Target
Fungal; Influenza Virus; SARS-CoV; Virus Protease
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/polycarpine-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=C(C=C1)C2=C(N(C(N)=N2)C)SSC3=C(N=C(N3C)N)C4=CC=C(C=C4)OC.Cl.Cl
Molecular Formula
C22H26Cl2N6O2S2
Molecular Weight
541.52
References & Citations
Pro
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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MCM9 (DNA Helicase MCM9, hMCM9, Mini-chromosome Maintenance Deficient Domain-containing Protein 1, Minichromosome Maintenance 9, C6orf61, MCMDC1, FLJ13942, FLJ20170, FLJ56845, MCMDC1, MGC35304, dJ329L24.1, dJ329L24.3) (HRP)
