FAP-IN-2

FAP-IN-2 is a derivative of 99mTc-labeled isonitrile-containing fibroblast activation protein (FAPI) inhibitor. FAP-IN-2 can be used for tumor imaging. FAP-IN-2 has good stability, high uptake and good retention in the tumor site of mouse model[1].

Product Specifications

CAS Number

[2471983-20-5]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

FAP

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/fap-in-2.html

Purity

99.93

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C(N1[C@@H](CC(F)(C1)F)C#N)CNC(C2=CC=NC3=C2C=C(OCCCN4CCNCC4)C=C3)=O

Molecular Formula

C24H28F2N6O3

Molecular Weight

486.51

Precautions

H302, H315, H319, H335

References & Citations

[1]Zhang JB, et al. Preparation method of technetium-99m-labeled isocyano-containing fibroblast activation protein inhibitor (FAPI) derivative for use as tumor imaging agent in nuclear medicine. China, CN112409414 A. 2021-02-26.