3’-O-t-Butyldimethylsilyladenosine
3’-O-t-Butyldimethylsilyladenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) [1].
Product Specifications
CAS Number
[69504-14-9]
UNSPSC
12352005
Hazard Statement
H302-H315-H320-H335
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/3-o-t-butyldimethylsilyladenosine.html
Solubility
10 mM in DMSO
Smiles
OC[C@@H]1[C@@H](O[Si](C)(C)C(C)(C)C)[C@@H](O)[C@H](N(C=N2)C3=C2C(N)=NC=N3)O1
Molecular Formula
C16H27N5O4Si
Molecular Weight
381.50
Precautions
P261-P280-P302+P352
References & Citations
[1]Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26 (6) :1490-1500.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
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