Antibacterial agent 185
Antibacterial agent 185 (compound IP-01) is a potent antibacterial agent. Antibacterial agent 185 inhibits filamentous temperature-sensitive mutant Z (FtsZ) polymerization and bundling by increasing GTP hydrolysis. Antibacterial agent 185 inhibits Streptococcus pneumoniae and shows narrow-spectrum activity[1].
Product Specifications
CAS Number
9007-83-4
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antibacterial-agent-185.html
Solubility
10 mM in DMSO
Smiles
CCOC(C1=C(N=C2C=CC(Br)=CN21)CSC3=CC=C(C=C3)OC)=O
Molecular Formula
C18H17BrN2O3S
Molecular Weight
421.31
References & Citations
[1]Jahan K, et al. Identification of ethyl-6-bromo-2 ((phenylthio) methyl) imidazo[1,2-a]pyridine-3-carboxylate as a narrow spectrum inhibitor of Streptococcus pneumoniae and its FtsZ. Eur J Med Chem. 2024 Mar 5;267:116196.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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