ADL-5747 (hydrochloride)
ADL-5747 hydrochloride is a selective and orally active agonist of the δ-opioid receptor (DOR) . By binding to the δ-opioid receptors, ADL-5747 hydrochloride activates these receptors, thereby playing a role in pain management pathways. ADL-5747 hydrochloride can be used for research into pain management mechanisms[1].
Product Specifications
CAS Number
1187653-56-0
UNSPSC
12352005
Target
Opioid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/adl-5747-hydrochloride.html
Smiles
CCN(C(C1=CC=C(C2=CC3(OC4=C2C=CC=C4)CCNCC3)C(O)=C1)=O)CC.Cl
Molecular Formula
C24H29ClN2O3
Molecular Weight
428.95
References & Citations
[1]Le Bourdonnec B, et al. Spirocyclic delta opioid receptor agonists for the treatment of pain: discovery of N, N-diethyl-3-hydroxy-4- (spiro [chromene-2, 4′-piperidine]-4-yl) benzamide (ADL5747) [J]. Journal of medicinal chemistry, 2009, 52 (18) : 5685-5702.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
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