SHEN26
SHEN26 (ATY014) is a potent and orally active RdRp inhibitor, with an IC50 for SARS-CoV-2 is 1.36 μM. SHEN26 is a 5’-cyclohexanecarboxylate derivative of GS-441524 (HY-103586) . SHEN26 inhibits viral nucleic acid synthesis to achieve antiviral effects. SHEN26 can be used for the research of coronavirus disease 2019 (COVID-19) [1][2].
Product Specifications
CAS Number
[2691076-98-7]
Product Name Alternative
ATV014
UNSPSC
12352005
Target
SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/shen26.html
Purity
99.10
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1CCCCC1)OC[C@@H]2[C@@H](O)[C@@H](O)[C@@](C3=CC=C4N3N=CN=C4N)(C#N)O2
Molecular Formula
C19H23N5O5
Molecular Weight
401.42
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Available Sizes
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