Endosidine 5

Endosidine 5 (ES5) inhibits EPS (extracellular polymeric substance) secretion and cell wall expansion. Endosidine 5 alters secretion of ECM (extracellular matrix) material in Penium margaritaceum by affecting the Golgi apparatus. Endosidine 5 interferes with recycling endosomes through Annexin A6, thereby promoting the release and expression of mRNA into the cytoplasm[1][2].

Product Specifications

CAS Number

[364361-68-2]

Product Name Alternative

ES5

UNSPSC

12352005

Target

Annexin A

Type

Reference compound

Related Pathways

Cytoskeleton

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/endosidine-5.html

Smiles

CC1=CC=C2C=C(C(N/N=C/C3=CNC4=C3C=CC=C4)=NC2=C1)C

Molecular Formula

C20H18N4

Molecular Weight

314.38

References & Citations

[1]LoRicco JG, et al. Endosidin 5 disruption of the Golgi apparatus and extracellular matrix secretion in the unicellular charophyte Penium margaritaceum. Ann Bot. 2023 Jul 10;131 (6) :967-983.|[2]Shin J, et al. Targeting Recycling Endosomes to Potentiate mRNA Lipid Nanoparticles. Nano Lett. 2024 May 1;24 (17) :5104-5109.