Endosidine 5
Endosidine 5 (ES5) inhibits EPS (extracellular polymeric substance) secretion and cell wall expansion. Endosidine 5 alters secretion of ECM (extracellular matrix) material in Penium margaritaceum by affecting the Golgi apparatus. Endosidine 5 interferes with recycling endosomes through Annexin A6, thereby promoting the release and expression of mRNA into the cytoplasm[1][2].
Product Specifications
CAS Number
364361-68-2
Product Name Alternative
ES5
UNSPSC
12352005
Target
Annexin A
Type
Reference compound
Related Pathways
Cytoskeleton
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/endosidine-5.html
Smiles
CC1=CC=C2C=C(C(N/N=C/C3=CNC4=C3C=CC=C4)=NC2=C1)C
Molecular Formula
C20H18N4
Molecular Weight
314.38
References & Citations
[1]LoRicco JG, et al. Endosidin 5 disruption of the Golgi apparatus and extracellular matrix secretion in the unicellular charophyte Penium margaritaceum. Ann Bot. 2023 Jul 10;131 (6) :967-983.|[2]Shin J, et al. Targeting Recycling Endosomes to Potentiate mRNA Lipid Nanoparticles. Nano Lett. 2024 May 1;24 (17) :5104-5109.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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