JG-48
JG-48 is a Hsp70 inhibitor that can reduce tau levels in models of tauopathy[1].
Product Specifications
CAS Number
[1627122-26-2]
UNSPSC
12352005
Target
HSP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/jg-48.html
Smiles
O=C1N(CC)/C(S/C1=C2SC3=CC(C(F)(F)F)=CC=C3N/2C)=C/C4=NC=CC=C4
Molecular Formula
C20H16F3N3OS2
Molecular Weight
435.49
References & Citations
[1]Young ZT, et al. Stabilizing the Hsp70-Tau Complex Promotes Turnover in Models of Tauopathy. Cell Chem Biol. 2016 Aug 18;23 (8) :992-1001.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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