Auxinole
Auxinole is a potent auxin antagonist of TIR1/AFB receptors, binding TIR1 to block the formation of the TIR1-IAA-Aux/IAA complex and so inhibits auxin-responsive gene expression.
Product Specifications
CAS Number
[86445-22-9]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/Auxinole.html
Purity
99.77
Solubility
DMSO : ≥ 125 mg/mL|Ethanol : 2.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(O)C(CC(C1=CC=C(C)C=C1C)=O)C2=CNC3=C2C=CC=C3
Molecular Formula
C20H19NO3
Molecular Weight
321.37
Precautions
H302, H315, H319, H335
References & Citations
[1]Hayashi K, et al. Rational design of an auxin antagonist of the SCF (TIR1) auxin receptor complex. ACS Chem Biol. 2012 Mar 16;7 (3) :590-8.|[2]Dindas J, et al. AUX1-mediated root hair auxin influx governs SCFTIR1/AFB-type Ca2+ signaling. Nat Commun. 2018 Mar 21;9 (1) :1174.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
