FT895
FT895 is a potent and selective HDAC11 inhibitor with an IC50 of 3 nM[1].
Product Specifications
CAS Number
2225728-57-2
UNSPSC
12352005
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/FT895.html
Concentration
10mM
Purity
99.84
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(NO)C1=C(CN(C2=CN=C(C(F)(F)F)C=N2)C3(C)C)C3=CC=C1
Molecular Formula
C16H15F3N4O2
Molecular Weight
352.31
References & Citations
[1]Martin MW, et al. Discovery of novel N-hydroxy-2-arylisoindoline-4-carboxamides as potent and selective inhibitors of HDAC11. Bioorg Med Chem Lett. 2018 Jul 1;28 (12) :2143-2147.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HDAC11
Available Sizes
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