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FT895

FT895 is a potent and selective HDAC11 inhibitor with an IC50 of 3 nM[1].

Product Specifications

CAS Number

[2225728-57-2]

UNSPSC

12352005

Target

HDAC

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

COVID-19-anti-virus

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/FT895.html

Concentration

10mM

Purity

99.84

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(NO)C1=C(CN(C2=CN=C(C(F)(F)F)C=N2)C3(C)C)C3=CC=C1

Molecular Formula

C16H15F3N4O2

Molecular Weight

352.31

References & Citations

[1]Martin MW, et al. Discovery of novel N-hydroxy-2-arylisoindoline-4-carboxamides as potent and selective inhibitors of HDAC11. Bioorg Med Chem Lett. 2018 Jul 1;28 (12) :2143-2147.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

HDAC11

Available Sizes

Curated Selection

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