E-0747
E-0747 is an antiarrhythmic drug that inhibits arrhythmias by inhibiting Na[+] channels in cardiomyocytes[1].
Product Specifications
CAS Number
[99599-78-7]
UNSPSC
12352005
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/e-0747.html
Smiles
O=C1NC2(C3=CC(Cl)=CC=C3OC(C)(C2)C)C(N1CCCN4CCC(CC4)O)=O
Molecular Formula
C21H28ClN3O4
Molecular Weight
421.92
References & Citations
[1]Mitsuhashi H, et al. Antiarrhythmic effects of a new drug, E-0747, on canine ventricular arrhythmia models. Jpn J Pharmacol. 1987 Jun;44 (2) :155-62.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-106749/E-0747-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-106749/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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