ITK ligand 1

ITK ligand 1 is a PROTAC target protein ligand (Ligand for Target Protein for PROTAC) . ITK ligand 1 can be used in the synthesis of PROTACs (e.g. HY-149917) [1].

Product Specifications

UNSPSC

12352005

Target

Itk; Ligands for Target Protein for PROTAC

Type

Reference compound

Related Pathways

PROTAC; Protein Tyrosine Kinase/RTK

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/itk-ligand-1.html

Smiles

O=C(NC1=CN([C@@H](CCCl)C2=CC=CC=C2)N=C1)C3=NNC4=C3CCC(C)(C)C4

Molecular Formula

C22H26ClN5O

Molecular Weight

411.93

References & Citations

[1]Zhou, et al. Discovery of Potent and Highly Selective Interleukin-2-Inducible T-Cell Kinase Degraders with In Vivo Activity. Journal of medicinal chemistry. 2023, 66 (7), 4979–4998.