ITK ligand 1
Product Specifications
UNSPSC Description
ITK ligand 1 is a PROTAC target protein ligand (Ligand for Target Protein for PROTAC). ITK ligand 1 can be used in the synthesis of PROTACs (e.g. HY-149917)[1].
Target Antigen
Itk; Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
PROTAC;Protein Tyrosine Kinase/RTK
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/itk-ligand-1.html
Smiles
O=C(NC1=CN([C@@H](CCCl)C2=CC=CC=C2)N=C1)C3=NNC4=C3CCC(C)(C)C4
Molecular Weight
411.93
References & Citations
[1]Zhou, et al. Discovery of Potent and Highly Selective Interleukin-2-Inducible T-Cell Kinase Degraders with In Vivo Activity. Journal of medicinal chemistry. 2023, 66(7), 4979–4998.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-168387/ITK-ligand-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-168387/
Clinical Information
No Development Reported
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