ITK ligand 1
ITK ligand 1 is a PROTAC target protein ligand (Ligand for Target Protein for PROTAC). ITK ligand 1 can be used in the synthesis of PROTACs (e.g. HY-149917).
Product Specifications
UNSPSC
12352005
Target
Itk; Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
PROTAC; Protein Tyrosine Kinase/RTK
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/itk-ligand-1.html
Smiles
O=C(NC1=CN([C@@H](CCCl)C2=CC=CC=C2)N=C1)C3=NNC4=C3CCC(C)(C)C4
Molecular Formula
C22H26ClN5O
Molecular Weight
411.93
References & Citations
[1]Zhou, et al. Discovery of Potent and Highly Selective Interleukin-2-Inducible T-Cell Kinase Degraders with In Vivo Activity. Journal of medicinal chemistry. 2023, 66 (7), 4979–4998.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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