CD209 Antibody / DC-SIGN
DC-SIGN/CD209 is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization, which allows the receptor to bind multivalent ligands with high avidity.
Product Specifications
CAS Number
9007-83-4
Specifications
Flow cytometry: 1-2ug/million cells
UniProt
Q9NNX6
Host
Mouse
Reactivity
Human
Immunogen
A recombinant human DC-SIGN/CD209 protein fragment was used as the immunogen for the CD209 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
C209/6774
Applications
FACS
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the CD209 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This CD209 antibody is available for research use only.
Storage Conditions
Aliquot the CD209 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the CD209 antibody should be determined by the researcher.
Location
Cell surface and secreted
Image Legend
SDS-PAGE analysis of purified, BSA-free CD209 antibody (clone C209/6774) as confirmation of integrity and purity.
Explore Other Products
Browse additional items from our catalog
TCAP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro)
