CART (Human, 55-102)

<strong>CART (Human, 55-102)</strong> <strong>Catalog number:</strong> MDP0721 <strong>CAS Number: </strong>624735-23-5 <strong>Sequence: </strong>Val-Pro-Ile-Tyr-Glu-Lys-Lys-Tyr-Gly-Gln-Val-Pro-Met-Cys-Asp-Ala-Gly-Glu-Gln-Cys-Ala-Val-Arg-Lys-Gly-Ala-Arg-Ile-Gly-Lys-Leu-Cys-Asp-Cys-Pro-Arg-Gly-Thr-Ser-Cys-Asn-Ser-Phe-Leu-Leu-Lys-Cys-Leu (Disulfide bonds between Cys68-Cys86, Cys74-Cys94, and Cys88-Cys101) <strong>Amount:</strong> 100 ug <strong>Molecular Weight:</strong> 5245.2 g/mol <strong>Supplied as:</strong> Powder <strong>Applications:</strong> molecular tool for various biochemical applications <strong>Storage:</strong> -20 °C <strong>WARNING:</strong> For in vitro Research Use Only. NOT for use on humans or animals. <strong>Grade:</strong> Biotechnology grade. All products are highly pure. <strong>References:</strong> 1: Matsumura K, Tsuchihashi T, Abe I. Central human cocaine- and amphetamine-regulated transcript peptide 55-102 increases arterial pressure in conscious rabbits Hypertension. 2001 Nov;38(5):1096-100. 2: Kozsurek M, Király K, Gyimesi K, Lukácsi E, Fekete C, Gereben B, Mohácsik P, Helyes Z, Bölcskei K, Tékus V, Pap K, Szűcs E, Benyhe S, Imre T, Szabó P, Gajtkó A, Holló K, Puskár Z. Unique, Specific CART Receptor-Independent Regulatory Mechanism of CART(55-102) Peptide in Spinal Nociceptive Transmission and Its Relation to Dipeptidyl-Peptidase 4 (DDP4) Int J Mol Sci. 2023 Jan 4;24(2):918. 3: Rakovska A, Baranyi M, Windisch K, Petkova-Kirova P, Gagov H, Kalfin R. Neurochemical evidence that cocaine- and amphetamine-regulated transcript (CART) 55-102 peptide modulates the dopaminergic reward system by decreasing the dopamine release in the mouse nucleus accumbens Brain Res Bull. 2017 Sep;134:246-252. 4: Dylag T, Kotlinska J, Rafalski P, Pachuta A, Silberring J. The activity of CART peptide fragments Peptides. 2006 Aug;27(8):1926-33. 5: Hubert GW, Jones DC, Moffett MC, Rogge G, Kuhar MJ. CART peptides as modulators of dopamine and psychostimulants and interactions with the mesolimbic dopaminergic system Biochem Pharmacol. 2008 Jan 1;75(1):57-62. 6: Murphy KG. Dissecting the role of cocaine- and amphetamine-regulated transcript (CART) in the control of appetite Brief Funct Genomic Proteomic. 2005 Jul;4(2):95-111. 7: Dun SL, Brailoiu E, Hsieh WK, Lai CC, Yang J, Chang JK, Dun NJ. Expression and activity of cocaine- and amphetamine-regulated transcript peptide(1-39) in the rat Regul Pept. 2007 Apr 5;140(1-2):47-54. 8: Kuhar MJ, Jaworski JN, Hubert GW, Philpot KB, Dominguez G. Cocaine- and amphetamine-regulated transcript peptides play a role in drug abuse and are potential therapeutic targets AAPS J. 2005 Sep 2;7(1):E259-65. 9: Job MO, McNamara IM, Kuhar MJ. CART Peptides Regulate Psychostimulants and May be Endogenous Antidepressants Curr Neuropharmacol. 2011 Mar;9(1):12-6. <a href="https://pubmed.ncbi.nlm.nih.gov/23174349">10: Blechová M, Nagelová V, Záková L, Demianová Z, Zelezná B, Maletínská L. New analogs of the CART peptide with anorexigenic potency: the importance of individual disulfide bridges Peptides. 2013 Jan;39:138-44. </a> <br><strong>Products Related to CART (Human, 55-102) can be found at</strong> <a href="https://moleculardepot.com/product-category/Peptides/"> Peptides</a>