Recombinant TOP2A Antibody / Topoisomerase II alpha
It recognizes a 170kDa protein, which is identified as topoisomerase II is also implicated in drug resistance of tumor cells and has been shown to be over-expressed in many human cancers. Decreased expression of Topo IIa is the predominant mechanism of resistance to several chemotherapeutic agents.
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 0.5-1 µg/mL
UniProt
P11388
Host
Mouse
Reactivity
Human, Mouse
Immunogen
A portion of amino acids 1352-1493 was used as the immunogen for the recombinant TOP2A antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG2a κ
Clone
RTOP2A/6569
Type
Recombinant
Applications
WB, IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the recombinant TOP2A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This recombinant TOP2A antibody is available for research use only.
Storage Conditions
Aliquot the recombinant TOP2A antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the recombinant TOP2A antibody should be determined by the researcher.
Location
Nuclear
Image Legend
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