Recombinant Mucin-1 Antibody / MUC1
Mucin-1 may provide a protective layer on epithelial cells against bacterial and enzyme attack. In immunohistochemical assays, it superbly stains routine formalin/paraffin carcinomas. Anti-Mucin-1 antibody is a useful marker for staining many carcinomas. It stains normal and neoplastic cells from various tissues, including mammary epithelium, sweat glands and colorectal carcinoma. Hepatocellular carcinoma, adrenal carcinoma and embryonal carcinomas are consistently Mucin-1 negative, so keratin positivity with negative Mucin-1 favors one of these tumors. Mucin-1 is frequently positive in meningioma, which can be useful when distinguishing it from other intracranial neoplasms such as schwannomas. Antibody to Mucin-1 is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver.
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
P15941
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant full-length human MUC1 protein was used as the immunogen for the recombinant Mucin-1 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG
Clone
MUC1/4416R
Type
Recombinant
Applications
WB, IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the recombinant Mucin-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This recombinant Mucin-1 antibody is available for research use only.
Storage Conditions
Aliquot the recombinant Mucin-1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the recombinant Mucin-1 antibody should be determined by the researcher.
Location
Cytoplasmic, Cell Surface
Image Legend
Documents
Frequently Asked Questions
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