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TRIM27 Antibody

Defects in TRIM27 are a cause of thyroid papillary carcinoma (TPC) . TPC is a common tumor of the thyroid that typically arises as an irregular, solid or cystic mass from otherwise normal thyroid tissue. Papillary carcinomas are malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells.

Product Specifications

CAS Number

9007-83-4

Specifications

Flow cytometry: 1-2ug/million cells, Immunofluorescence: 1-2 µg/mL

UniProt

P14373

Host

Mouse

Reactivity

Human

Immunogen

Recombinant full-length human TRIM27 protein was used as the immunogen for the TRIM27 antibody.

Clonality

Monoclonal

Isotype

IgG2a

Clone

PCRP-TRIM27-1B3

Applications

FACS, IF

Purity

Protein A/G affinity

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Aliquot the TRIM27 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This TRIM27 antibody is available for research use only.

Storage Conditions

Aliquot the TRIM27 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Applications Notes

Optimal dilution of the TRIM27 antibody should be determined by the researcher.

Location

Nucleus, Cytoplasm

Image Legend

Immunofluorescent staining of PFA-fixed U87 cells using TRIM27 antibody (green, clone PCRP-TRIM27-1B3) and phalloidin (red) .

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