Leptin Receptor Antibody / LEPR / Ob-R

The Ob gene encodes the protein leptin. The leptin receptor, designated Ob-R, has been shown to be a single membrane-spanning receptor that most resembles the gp130 signal transducing component of the IL-6, G-CSF and LIF receptor.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL

UniProt

P48357

Host

Mouse

Reactivity

Human

Immunogen

A portion of amino acids 335-425 was used as the immunogen for the Leptin Receptor antibody.

Clonality

Monoclonal

Isotype

IgG1 k

Clone

LEPR/4301

Applications

IHC-P

Purity

Protein A/G affinity

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Aliquot the Leptin Receptor antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Leptin Receptor antibody is available for research use only.

Storage Conditions

Aliquot the Leptin Receptor antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Applications Notes

Optimal dilution of the Leptin Receptor antibody should be determined by the researcher.

Location

Secreted, Cell surface

Image Legend

Analysis of HuProt (TM) microarray containing more than 19,000 full-length human proteins using Leptin Receptor antibody (clone LEPR/4301) . These results demonstrate the foremost specificity of the LEPR/4301 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt (TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt (TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.