Recombinant Delta 1 Catenin Antibody / CTNND1 / p120 Catenin

Alpha-catenin and beta-catenin bind to the intracellular domain of E-cadherin while p120 catenin (delta-1-catenin) binds E-cadherin at a juxta-membrane site. The complex stabilizes tight junctions. In the cell, delta-1-catenin localized to the E-cadherin/catenins cell adhesion complex, directly associates with cytoplasmic C-terminus of E-cadherin and may similarly interact with other cadherins.

Product Specifications

CAS Number

9000-83-3

Specifications

Immunohistochemistry (FFPE) : 2-4 µg/mL

UniProt

O60716

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 900-1,000 was used as the immunogen for the recombinant Delta 1 Catenin antibody.

Clonality

Recombinant Monoclonal

Isotype

IgG

Clone

CTNND1/4383R

Type

Recombinant

Applications

IHC-P

Purity

Protein A/G affinity

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Aliquot the recombinant Delta 1 Catenin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This recombinant Delta 1 Catenin antibody is available for research use only.

Storage Conditions

Aliquot the recombinant Delta 1 Catenin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Applications Notes

Optimal dilution of the recombinant Delta 1 Catenin antibody should be determined by the researcher.

Location

Cell Surface, Cytoplasm

Image Legend

IHC staining of FFPE human colon tissue with recombinant Delta 1 Catenin antibody (clone CTNND1/4383R) at 2ug/ml in PBS for 30min RT. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.