TOM1L1 Antibody
Tom1 (target of Myb 1) is a 492 amino acid cytoplasmic protein that belongs to the Tom1 family. Widely expressed with highest expression in heart, liver, placenta and skeletal muscle, Tom1 is thought to be involved in intracellular trafficking and may be associated with the translocation of ubiquitinated proteins to early endosomes for degradation. Tom1 contains one GAT domain and one VHS domain through which it interacts and complexes with proteins such as Tollip and endofin (also known as SARA) . These interactions recruit Tom1 to the endosome, allowing it to participate in the endosomal trafficking of ubiquitin-tagged proteins.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 2-4 µg/mL
UniProt
O75674
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full-length human TOM1L1 protein was used as the immunogen for the TOM1L1 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
TOM1L1/4690
Applications
IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the TOM1L1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This TOM1L1 antibody is available for research use only.
Storage Conditions
Aliquot the TOM1L1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the TOM1L1 antibody should be determined by the researcher.
Location
Cytoplasm
Image Legend
Documents
Frequently Asked Questions
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