Recombinant Mammaglobin A Antibody / SCGB2A2

Mammaglobin, 10 kDa, is a cytoplasmic protein, a mammary-specific member of the uteroglobin family. It is related to a family of epithelial secretory proteins that includes prostatein and Clara cell protein. Mammaglobin occurs in about 80% of breast carcinomas. The extend is generally larger than that of GCDFP-15. Up to 15% of non-breast carcinomas (such as stomach, lung, colon, hepatobiliary, thyroid, ovarian, and urothelial carcinomas) have been reported positive, usually only focally. Mammaglobin is a sensitive and fairly specific marker for breast carcinoma. The panel should also include Gross cystic disease fluid protein-15 and Estrogen receptor alpha.

Product Specifications

CAS Number

9000-83-3

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL

UniProt

Q13296

Host

Mouse

Reactivity

Human

Immunogen

Recombinant full-length human Mammaglobin/SCGB2A2 protein was used as the immunogen for the recombinant Mammaglobin A antibody.

Clonality

Recombinant Monoclonal

Isotype

IgG1 k

Clone

RMGB/6619

Type

Recombinant

Applications

IHC-P

Purity

Protein A/G affinity

Format

Purified

Buffer

1 mg/ml in 1X PBS; BSA free, sodium azide free

Reconstitution

Aliquot the recombinant Mammaglobin A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This recombinant Mammaglobin A antibody is available for research use only.

Storage Conditions

Aliquot the recombinant Mammaglobin A antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

1 mg/mL in 1X PBS; BSA free, sodium azide free

Applications Notes

Optimal dilution of the recombinant Mammaglobin A antibody should be determined by the researcher.

Location

Cytoplasm

Image Legend

IHC staining of FFPE human lactating breast tissue with recombinant Mammaglobin A antibody (clone rMGB/6619) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.