LMO2 Antibody / Rhombotin 2
The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. It has a particular function in normal and lymphatic endothelial cells involving the regulation of angiogenesis and lymph-angiogenesis. Immunohistochemical studies have also demonstrated expression of LMO2 in both normal germinal center B-cells and germinal center-derived B-cell lymphomas, including follicular lymphoma and diffuse large B-cell lymphoma.The use of anti-LMO2 is valuable as a tool in the identification of lymphomas of B-cell origin.LMO2 is useful in differentiating follicular lymphoma (LMO2+) from nodal marginal zone lymphoma (LM02-) . It also is positive in Hodgkin s and Burkitt s lymphomas.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
P25791
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 23-140 was used as the immunogen for the LMO2 antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
LMO2/1972
Applications
IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the LMO2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This LMO2 antibody is available for research use only.
Storage Conditions
Aliquot the LMO2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the LMO2 antibody should be determined by the researcher.
Location
Nucleus, Cytoplasm, Cell surface
Image Legend
Frequently Asked Questions
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