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Recombinant Napsin A Antibody

Napsin is a pepsin-like aspartic proteinase connected with maturation of surfactant protein B. There are two closely related napsins, napsin A and napsin B. Napsin A is expressed as a single chain protein. Immunohistochemical studies revealed high expression levels of napsin A in human lung and kidney but low expression in spleen. Napsin A is expressed in type II pneumocytes and in adenocarcinomas of lung. The high specificity expression of napsin A in adenocarcinomas of lung is useful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs.

Product Specifications

CAS Number

9000-83-3

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL, Western blot: 2-4 µg/mL

UniProt

O96009

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids1-100 was used as the immunogen for the recombinant Napsin A antibody.

Clonality

Recombinant Monoclonal

Isotype

IgG κ

Clone

NAPSA/7043R

Type

Recombinant

Applications

IHC-P, WB

Purity

Protein A affinity

Format

Purified

Buffer

1 mg/ml in 1X PBS; BSA free, sodium azide free

Reconstitution

Aliquot the recombinant Napsin A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This recombinant Napsin A antibody is available for research use only.

Storage Conditions

Aliquot the recombinant Napsin A antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

1 mg/mL in 1X PBS; BSA free, sodium azide free

Applications Notes

Optimal dilution of the recombinant Napsin A antibody should be determined by the researcher.

Location

Cytoplasm

Image Legend

Western blot testing of human kidney tissue lysate with recombinant Napsin A antibody. Expected molecular weight: 38-45 kDa.

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