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Anti-UchL1 Antibody

This mAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1) . Initially, UchL1 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for UchL1 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in the gene is believed to cause a form of Parkinson's disease.

Product Specifications

Specifications

Western blot: 1-2 µg/mL

UniProt

P09936

Host

Mouse

Reactivity

Human

Immunogen

Native UchL1/PGP9.5 protein isolated from human brain was used as the immunogen for this anti-UchL1 antibody.

Clonality

Monoclonal

Isotype

IgG2a κ

Clone

SPM575

Applications

WB

Purity

Protein G affinity chromatography

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Reconstitution

Store the anti-UchL1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This anti-UchL1 antibody is available for research use only.

Storage Conditions

Store the anti-UchL1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Product Datasheet

https://www.nsjbio.com/tds-pdf/anti-uchl1-antibody-spm575-v9097

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide

Applications Notes

The optimal dilution of the anti-UchL1 antibody for each application should be determined by the researcher.

CAS Number

9007-83-4

Location

Cytoplasmic. Endoplasmic Reticulum membrane

Image Legend

Western blot testing of human brain lysate with anti-UchL1 antibody (clone SPM575) . Predicted molecular weight ~25 kDa.

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