RBP Antibody
Recognizes a protein of 21kDa-25kDa, identified as retinol binding protein (RBP) . Its epitope localizes between aa 74-182 of human RBP. This MAb recognizes reduced and carboxy-methylated RBP (RCM-RBP) as well as the circulatory RBP but not the native RBP, thereby suggesting that its epitope becomes accessible either on unfolding or upon binding of RBP to transthyretin (prealbumin) .</strong> RBP is responsible for distributing retinol from the retinoid stores in the liver to the various target tissues. Once secreted into the blood with bound retinol, the vitamin carrier circulates complexed with transthyretin prior to vitamin delivery at the plasma membrane through a receptor-mediated mechanism.
Product Specifications
CAS Number
9007-83-4
Specifications
UniProt
P02753, P09455, P50120
Host
Mouse
Reactivity
Human
Immunogen
Clonality
Monoclonal
Isotype
IgG1 k
Clone
SPM442
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
Reconstitution
Store the RBP antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This RBP antibody is available for research use only.
Storage Conditions
Store the RBP antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*
Location
Cytoplasmic
Image Legend
IHC: Formalin-fixed, paraffin-embedded human hepatocellular carcinoma stained with RBP (clone SPM442) .
Frequently Asked Questions
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