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Anti-Prolactin Receptor Antibody

It recognizes a protein of 70kDa, identified as prolactin receptor. Prolactin is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. The initial step in its action is the binding to a specific membrane receptor (prolactin receptor), which belongs to the superfamily of class 1 cytokine receptors. The function of the prolactin receptor is mediated, at least in part, by two families of signaling molecules: Janus kinases and signal transducers and activators of transcription.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT

UniProt

P16471

Host

Mouse

Reactivity

Human

Immunogen

Semi-purified human prolactin receptor was used as the immunogen for this anti-Prolactin Receptor antibody.

Clonality

Monoclonal

Isotype

IgG1 k

Clone

SPM213

Applications

IHC-P

Purity

Protein G affinity chromatography

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Reconstitution

Store the anti-Prolactin Receptor antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This anti-Prolactin Receptor antibody is available for research use only.

Storage Conditions

Store the anti-Prolactin Receptor antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide

Location

Cell surface and cytoplasmic

Image Legend

IHC: Formalin-fixed, paraffin-embedded human testicular carcinoma stained with anti-Prolactin Receptor antibody (SPM213) .

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